Using kernelized partial canonical correlation analysis to study directly coupled side chains and allostery in small G proteins
نویسندگان
چکیده
منابع مشابه
Using kernelized partial canonical correlation analysis to study directly coupled side chains and allostery in small G proteins
MOTIVATION Inferring structural dependencies among a protein's side chains helps us understand their coupled motions. It is known that coupled fluctuations can reveal pathways of communication used for information propagation in a molecule. Side-chain conformations are commonly represented by multivariate angular variables, but existing partial correlation methods that can be applied to this in...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2015
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btv241